BDBM50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE
SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
InChI Key InChIKey=MCMMCRYPQBNCPH-DVKRWUGUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 77 hits for monomerid = 50001683
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DPDPE from mouse whole brain DORMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]Cl-DPDPE from human DOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-IBNtxA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]C1-DPDPE from human recombinant Opioid receptor delta 1 on CHO cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-IBNalA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (1-3.9)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:In vitro potency was measured against human Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]DPDPE from Sprague-Dawley rat delta opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain homogenates, using [3H]DPDPE as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of [3H]- [D-Pen2, D-Pen5]-enkephalin (DPDPE) binding to Opioid receptor delta 1 in guinea pig brain homogenate...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]DSLET binding to delta 1 opioid receptors in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]-DTLET binding torat brain membrane Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Tested for binding affinity against delta opioid receptor by displacing [3H]- DSLET radioligand from rat brain membrane preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLETMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Compound was evaluated for the binding affinity in comparison with [3H]-[p-Cl-Phe4]-DPDPE (opioid receptor delta selective ligand)More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against forskolin-stimulated cAMP production in chinese hamster ovary cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Compound is tested in vitro in mouse vas deferens (MVD) assay mediated by Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Opioid receptor binding affinity in rat brain membrane preparations by the displacement of [3H]DSLET (Opioid receptor delta 1-selective radioligand)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity measured against Opioid receptor delta 1 using mouse vas deference assay (MVD).More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity measured against [3H]DPDPE (Opioid receptor delta 1 ligand) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Ability to displace [3H]DPDPE from Opioid receptor delta 1 in rat brain membranes, was determined from radioreceptor assay.More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Tested for agonist activity against delta opioid receptor mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Binding affinity towards Opioid receptor delta 1 was determined in guinea pig wholebrain using [3H][4''-Cl-Phe4]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration was determined against delta-opioid receptor using [3H]- DPDPE radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for the binding affinity against the Delta opioid receptor in guinea pig brain using [3H]DPDPEMore data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of radioligand [3H][p-Cl-phe]-DPDPE to Opioid receptor delta 1 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory potency against Opioid receptor delta 1 was determined in electrically induced smooth muscle contractions of mouse vas deferens (MVD)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]-p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Binding affinity towards delta opioid receptor was determined in rat brain using [H]-[p-Cl-Phe4]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human delta opioid receptor expressed in mouse HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair